Research workbench
AlphaFold monomer V2.0 prediction for transportin-1 (Q92973)
Analyse AlphaFold monomer V2.0 prediction for transportin-1 (Q92973) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q92973
- Type
- protein
- Length
- 898 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- Transportin-1
- UniProt
- Q92973
- Pockets
- 8 · best druggability 0.80
Structure
1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transportin-1 | protein | 898 | 75% helix, 0% strand | Q92973 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 966 | 0.80 | 0.82 | 81 | empty |
| 2 | 95 | 0.43 | 0.79 | 14 | empty |
| 3 | 109 | 0.39 | 0.76 | 23 | empty |
| 4 | 51 | 0.31 | 0.76 | 13 | empty |
| 5 | 60 | 0.29 | 0.75 | 15 | empty |
Compared structures
- 4FDD · Crystal structure of kap BETA2-py-nls · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 4FDD · Crystal structure of KAP beta2-PY-NLS · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 2Z5K · Complex of transportin 1 with tap nls · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2Z5K · Complex of Transportin 1 with TAP NLS · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 7CYL · Crystal structure of karyopherin-BETA2 in complex with fus py- NLS(P525L) · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2Z5N · Complex of Transportin 1 with hnRNP D NLS · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2Z5N · Complex of transportin 1 with hnrnp D nls · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 5J3V · Crystal structure of human karyopherin-BETA2 bound to the histone H3 tail · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4FQ3 · Crystal structure of TRANSPORTIN/FUS-nls · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4FQ3 · Crystal structure of transportin/FUS-NLS · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 5YVI · Crystal structure of karyopherin BETA2 in complex with FUS(456-526) · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 5YVG · Crystal structure of Karyopherin beta2 in complex with FUS(full length) · an experimental structure of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92973
- Elsewhere: UniProt Q92973 · AlphaFold DB Q92973
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