Research workbench
AlphaFold monomer V2.0 prediction for protein THP3 (Q12049)
Analyse AlphaFold monomer V2.0 prediction for protein THP3 (Q12049) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q12049
- Type
- protein
- Length
- 470 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Protein THP3
- UniProt
- Q12049
- Pockets
- 4 · best druggability 0.77
Structure
1 distinct chain · 46% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein THP3 | protein | 470 | 46% helix, 4% strand | Q12049 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 911 | 0.77 | 0.80 | 69 | empty |
| 2 | 566 | 0.66 | 0.76 | 47 | empty |
| 3 | 125 | 0.46 | 0.78 | 20 | empty |
| 4 | 57 | 0.39 | 0.80 | 15 | empty |
Compared structures
- 7EWM · Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1 · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 7EWF · Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and… · an experimental structure of the same protein · chain A against A, TM-score 0.56
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12049
- Elsewhere: UniProt Q12049 · AlphaFold DB Q12049
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