AlphaFold monomer V2.0 prediction for tubulin alpha-1B chain (P81947)

Structure

1 distinct chain · 45% helix, 17% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 6RFD · Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence)… · an experimental structure of the same protein · chain A against A, TM-score 0.95
• 6WVL · Low curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule · an experimental structure of the same protein · chain A against C, TM-score 0.95
• 6GJ4 · Tubulin-6j complex · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 4YJ3 · Crystal structure of tubulin bound to compound 2 · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 6Y6D · Tubulin-7-Aminonoscapine complex · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 8WD0 · Crystal structure of T2R-TTL-Erianin complex · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 8CLH · Drug cocktail (Colchicine, Epothilone A, Peloruside, Ansamitocin P3, Vinblastine) bound… · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 5BMV · CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 4O2B · Tubulin-Colchicine complex · an experimental structure of the same protein · chain A against C, TM-score 0.94
• 6FJF · Tubulin-FcMaytansine complex · an experimental structure of the same protein · chain A against C, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P81947
• Elsewhere: UniProt P81947 · AlphaFold DB P81947