AlphaFold monomer V2.0 prediction for tyrosine--tRNA ligase, cytoplasmic (P54577)

Structure

1 distinct chain · 39% helix, 21% strand (DSSP).

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 7ROU · Structure of human tyrosyl tRNA synthetase in complex with ML901-tyr · an experimental structure of the same protein · chain A against A, TM-score 0.63
• 7ROU · Structure of human tyrosyl tRNA synthetase in complex with ML901-Tyr · an experimental structure of the same protein · chain A against A, TM-score 0.63
• 5THH · Crystal structure of a human tyrosyl-tRNA synthetase mutant · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 1Q11 · Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 1Q11 · Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 4QBT · Crystal structure of tyrosine bound human tyrosyl tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 4QBT · Crystal structure of tyrosine bound human tyrosyl tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 1N3L · Crystal structure of a human aminoacyl-tRNA synthetase cytokine · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 1N3L · Crystal structure of a human aminoacyl-tRNA synthetase cytokine · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 4Q93 · Crystal structure of resveratrol bound human tyrosyl tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 4Q93 · Crystal structure of resveratrol bound human tyrosyl tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 5THL · Crystal structure of the human tyrosyl-tRNA synthetase mutant G41R · an experimental structure of the same protein · chain A against A, TM-score 0.60

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P54577
• Elsewhere: UniProt P54577 · AlphaFold DB P54577