Research workbench
AlphaFold monomer V2.0 prediction for valine--tRNA ligase (P96142)
Analyse AlphaFold monomer V2.0 prediction for valine--tRNA ligase (P96142) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P96142
- Type
- protein
- Length
- 862 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x09067B755dA348BB0cd7Bf29E7A2740929Aa7F75
- Molecule
- Valine--tRNA ligase
- UniProt
- P96142
- Pockets
- 8 · best druggability 0.78
Structure
1 distinct chain · 49% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Valine--tRNA ligase | protein | 862 | 49% helix, 18% strand | P96142 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 674 | 0.78 | 0.83 | 58 | empty |
| 2 | 368 | 0.63 | 0.78 | 43 | empty |
| 3 | 255 | 0.62 | 0.81 | 27 | empty |
| 4 | 50 | 0.48 | 0.86 | 19 | empty |
| 5 | 105 | 0.37 | 0.75 | 18 | empty |
Compared structures
- 1IYW · Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 1IYW · Preliminary structure of thermus thermophilus ligand-free valyl-tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 1IVS · Crystal structure of thermus thermophilus valyl-tRNA synthetase complexed with TRNA(VAL)… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1IVS · Crystal structure of thermus thermophilus valyl-tRNA synthetase complexed with TRNA(VAL)… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1GAX · Crystal structure of thermus thermophilus valyl-tRNA synthetase complexed with TRNA(VAL)… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1GAX · Crystal structure of thermus thermophilus valyl-tRNA synthetase complexed with TRNA(VAL)… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1WKA · Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase… · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 1WKA · Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase… · an experimental structure of the same protein · chain A against A, TM-score 0.17
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96142
- Elsewhere: UniProt P96142 · AlphaFold DB P96142
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