MolNFT v1 · #26278 · protein
Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain
1WKA: “Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain”. X-ray diffraction, 1 pocket (best druggability 0.49). MolNFT v1 #26278 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1WKA
- Type
- protein
- Length
- 143 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Valyl-tRNA synthetase
- EC
- 6.1.1.9
- UniProt
- P96142
- Pockets
- 1 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Valyl-tRNA synthetase (EC 6.1.1.9) | protein | 143 | 26% helix, 29% strand | P96142 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.49 | 0.78 | 23 | empty |
Compared structures
- 1WKA · Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase… · the same entry in another collection · chain A against A, TM-score 1.00
- P96142 · AlphaFold monomer V2.0 prediction for valine--tRNA ligase (P96142) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96142
- Elsewhere: RCSB PDB 1WKA · PDBe 1WKA · UniProt P96142
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