AlphaFold monomer V2.0 prediction for synaptotagmin-1 (P21579)

Structure

1 distinct chain · 20% helix, 31% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 2R83 · Crystal structure analysis of human synaptotagmin 1 C2A-C2B · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 2R83 · Crystal structure analysis of human synaptotagmin 1 C2A-C2B · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 4V11 · Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 4V11 · Structure of synaptotagmin-1 with SV2A peptide phosphorylated at THR84 · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6U4W · 1.4 A structure of a pathogenic human Syt 1 C2B (D366E) · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6U4W · 1.4 a structure of a pathogenic human syt 1 C2B (D366E) · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6TZ3 · Crystal structure of human synaptotagmin 1 C2B without CA2+ · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6TZ3 · Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6U4U · 1.3 A structure of a pathogenic human Syt 1 C2B (I368T) · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 6U4U · 1.3 a structure of a pathogenic human syt 1 C2B (I368T) · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 2N1T · Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution · an experimental structure of the same protein · chain A against E, TM-score 0.35
• 2N1T · Dynamic binding mode of a synaptotagmin-1-snare complex in solution · an experimental structure of the same protein · chain A against E, TM-score 0.35

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P21579
• Elsewhere: UniProt P21579 · AlphaFold DB P21579