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AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q8PMP0)

Analyse AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q8PMP0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8PMP0
Type
protein
Length
694 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x953a45c1afa6C5147a9c9dE66B77afE523F6E050
Molecule
Methionine--tRNA ligase
UniProt
Q8PMP0
Pockets
3 · best druggability 0.73

Structure

1 distinct chain · 42% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMethionine--tRNA ligaseprotein69442% helix, 19% strandQ8PMP0

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17840.730.7877empty
2520.560.9026empty
32020.450.7326empty

Compared structures

  • 6WQ6 · Xanthomonas citri Methionyl-tRNA synthetase in complex with methionine · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQ6 · Xanthomonas citri methionyl-tRNA synthetase in complex with methionine · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQT · Xanthomonas citri methionyl-tRNA synthetase in complex with REP3123 · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQT · Xanthomonas citri Methionyl-tRNA synthetase in complex with REP3123 · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQI · Xanthomonas citri Methionyl-tRNA synthetase (apo) · an experimental structure of the same protein · chain A against B, TM-score 0.78
  • 6WQI · Xanthomonas citri methionyl-tRNA synthetase (apo) · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQS · Xanthomonas citri Methionyl-tRNA synthetase in complex with REP8839 · an experimental structure of the same protein · chain A against A, TM-score 0.78
  • 6WQS · Xanthomonas citri methionyl-tRNA synthetase in complex with REP8839 · an experimental structure of the same protein · chain A against A, TM-score 0.78

Analyse

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