Research workbench
AlphaFold monomer V2.0 prediction for lysine--tRNA ligase (Q15046)
Analyse AlphaFold monomer V2.0 prediction for lysine--tRNA ligase (Q15046) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q15046
- Type
- protein
- Length
- 597 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Lysine--tRNA ligase
- UniProt
- Q15046
- Pockets
- 8 · best druggability 0.79
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lysine--tRNA ligase | protein | 597 | 36% helix, 21% strand | Q15046 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 853 | 0.79 | 0.82 | 81 | empty |
| 2 | 358 | 0.57 | 0.75 | 44 | empty |
| 3 | 92 | 0.44 | 0.79 | 20 | empty |
| 4 | 66 | 0.37 | 0.78 | 12 | empty |
| 5 | 53 | 0.33 | 0.78 | 15 | empty |
Compared structures
- 4DPG · Crystal structure of human lysrs: P38/AIMP2 complex I · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 4DPG · Crystal Structure of Human LysRS: P38/AIMP2 Complex I · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 4YCU · Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 4YCU · Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 6ILH · Crystal structure of human lysyl-tRNA synthetase L350H mutant · an experimental structure of the same protein · chain A against B, TM-score 0.84
- 6ILH · Crystal Structure of human lysyl-tRNA synthetase L350H mutant · an experimental structure of the same protein · chain A against B, TM-score 0.84
- 3BJU · Crystal Structure of tetrameric form of human lysyl-tRNA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15046
- Elsewhere: UniProt Q15046 · AlphaFold DB Q15046
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