Research workbench
AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2B (Q7L1I2)
Analyse AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2B (Q7L1I2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q7L1I2
- Type
- protein
- Length
- 683 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Synaptic vesicle glycoprotein 2B
- UniProt
- Q7L1I2
- Pockets
- 7 · best druggability 0.76
Structure
1 distinct chain · 61% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Synaptic vesicle glycoprotein 2B | protein | 683 | 61% helix, 9% strand | Q7L1I2 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 573 | 0.76 | 0.83 | 64 | empty |
| 2 | 55 | 0.72 | 0.99 | 18 | empty |
| 3 | 494 | 0.64 | 0.76 | 54 | empty |
| 4 | 124 | 0.47 | 0.79 | 23 | empty |
| 5 | 95 | 0.40 | 0.77 | 20 | empty |
Compared structures
- 8UO8 · Structure of synaptic vesicle protein 2B with padsevonil · an experimental structure of the same protein · chain A against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7L1I2
- Elsewhere: UniProt Q7L1I2 · AlphaFold DB Q7L1I2
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