UniProt Q7L1I2
Synaptic vesicle glycoprotein 2B (Q7L1I2)
Synaptic vesicle glycoprotein 2B (UniProt Q7L1I2): 1 experimental structure and 1 predicted model on GenesisL1, 6 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7L1I2
- Protein
- Synaptic vesicle glycoprotein 2B
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 13 · 2 records with a druggable one
Structures
2 records of Q7L1I2 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UO8 | Structure of synaptic vesicle protein 2B with padsevonil | electron microscopy | A | NAG, X3U, PS1, 9Z9, 43Y, Y01 | 6 (best 0.84) |
| Q7L1I2 | AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2B (Q7L1I2) | predicted | A | — | 7 (best 0.76) |
Ligands
- 43Y · [(2R)-3-[oxidanyl-[2-(trimethyl-$L^{4}-azanyl) ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoate · in 1 record
- 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- PS1 · 1,2-didecanoyl-sn-glycero-3-[phospho-L-serine] · in 1 record
- X3U · (4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Experiment against prediction
- 8UO8 chain A against the predicted model Q7L1I2: TM-score 0.94, RMSD 2.59 Å
Elsewhere
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