Research workbench
AlphaFold monomer V2.0 prediction for succinate--CoA ligase [GDP- forming] subunit beta, mitochondrial (Q96I99)
Analyse AlphaFold monomer V2.0 prediction for succinate--CoA ligase [GDP- forming]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q96I99
- Type
- protein
- Length
- 432 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- UniProt
- Q96I99
- Pockets
- 2 · best druggability 0.70
Structure
1 distinct chain · 35% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | protein | 432 | 35% helix, 23% strand | Q96I99 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 708 | 0.70 | 0.77 | 66 | empty |
| 2 | 71 | 0.28 | 0.72 | 16 | empty |
Compared structures
- 8Z02 · CoA bound to human GTP-specific succinyl-CoA synthetase · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 7MST · Phosphorylated human E105Qa GTP-specific succinyl-CoA synthetase complexed with coenzyme A · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 6WCV · Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase · an experimental structure of the same protein · chain A against B, TM-score 0.88
- 6WCV · Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase · an experimental structure of the same protein · chain A against B, TM-score 0.88
- 8Z03 · Lactate bound to human GTP-specific succinyl-CoA synthetase · an experimental structure of the same protein · chain A against B, TM-score 0.88
- 7MSS · Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinate, magnesium ion… · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 7MSR · Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate… · an experimental structure of the same protein · chain A against B, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96I99
- Elsewhere: UniProt Q96I99 · AlphaFold DB Q96I99
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