Research workbench
AlphaFold monomer V2.0 prediction for probable global transcription activator SNF2L2 (P51531)
Analyse AlphaFold monomer V2.0 prediction for probable global transcription activator… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P51531
- Type
- protein
- Length
- 1,590 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6F1477A7ba7b4D12E5dE4da4526a61F2AFaa8749
- Molecule
- Probable global transcription activator SNF2L2
- UniProt
- P51531
- Pockets
- 12 · best druggability 0.75
Structure
1 distinct chain · 41% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable global transcription activator SNF2L2 | protein | 1590 | 41% helix, 5% strand | P51531 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 502 | 0.75 | 0.83 | 69 | empty |
| 2 | 467 | 0.71 | 0.81 | 55 | empty |
| 3 | 638 | 0.68 | 0.77 | 54 | empty |
| 4 | 353 | 0.61 | 0.77 | 36 | empty |
| 5 | 90 | 0.55 | 0.85 | 16 | empty |
Compared structures
- 6EG3 · Crystal structure of human brm in complex with compound 15 · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 6EG2 · Crystal structure of human brm in complex with compound 16 · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 6HAY · Crystal structure of PROTAC 1 in complex with the bromodomain of human SMARCA2 and… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6HAY · Crystal structure of protac 1 in complex with the bromodomain of human SMARCA2 and… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6HAX · Crystal structure of protac 2 in complex with the bromodomain of human SMARCA2 and… · an experimental structure of the same protein · chain A against E, TM-score 0.08
- 2DAT · Solution structure of the bromodomain of human SWI/SNF related matrix associated actin… · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2DAT · Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin… · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 5DKH · Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 5DKH · Crystal structure of the bromodomain of human brm (SMARCA2) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51531
- Elsewhere: UniProt P51531 · AlphaFold DB P51531
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