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AlphaFold monomer V2.0 prediction for structure-specific endonuclease subunit SLX1 (Q6FML9)

Analyse AlphaFold monomer V2.0 prediction for structure-specific endonuclease subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q6FML9
Type
protein
Length
312 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x47E832BB26b49F1eEbE3dD4A804024b1195017F7
Molecule
Structure-specific endonuclease subunit SLX1
UniProt
Q6FML9
Pockets
5 · best druggability 0.58

Structure

1 distinct chain · 40% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AStructure-specific endonuclease subunit SLX1protein31240% helix, 15% strandQ6FML9

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12520.580.7940empty
21890.510.7726empty
31470.420.7424empty
41270.420.7619empty
5850.400.7815empty

Compared structures

  • 4XLG · C. glabrata Slx1 in complex with Slx4CCD. · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 4XLG · C. glabrata SLX1 in complex with SLX4CCD. · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 4XM5 · C. glabrata Slx1. · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 4XM5 · C. glabrata SLX1. · an experimental structure of the same protein · chain A against A, TM-score 0.82

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