Research workbench
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SIK3 (Q9Y2K2)
Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SIK3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9Y2K2
- Type
- protein
- Length
- 1,321 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x02df3F8069b24076E54c06706a40f151233Ec8EE
- Molecule
- SERINE/THREONINE-protein kinase SIK3
- UniProt
- Q9Y2K2
- Pockets
- 5 · best druggability 0.78
Structure
1 distinct chain · 20% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase SIK3 | protein | 1321 | 20% helix, 4% strand | Q9Y2K2 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 963 | 0.78 | 0.80 | 73 | empty |
| 2 | 772 | 0.72 | 0.78 | 73 | empty |
| 3 | 218 | 0.57 | 0.79 | 31 | empty |
| 4 | 90 | 0.38 | 0.76 | 15 | empty |
| 5 | 58 | 0.29 | 0.74 | 13 | empty |
Compared structures
- 8OKU · Salt-Inducible Kinase 3 in complex with an inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 8R4O · Salt inducible kinase 3 in complex with inhibitor · an experimental structure of the same protein · chain A against G, TM-score 0.24
- 8R4V · Structure of Salt-inducible kinase 3 in complex with inhibitor · an experimental structure of the same protein · chain A against C, TM-score 0.24
- 8R4Q · Salt inducible kinase 3 in complex with inhibitor · an experimental structure of the same protein · chain A against G, TM-score 0.24
- 8R4U · Structure of salt-inducible kinase 3 with inhibitors · an experimental structure of the same protein · chain A against A, TM-score 0.24
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y2K2
- Elsewhere: UniProt Q9Y2K2 · AlphaFold DB Q9Y2K2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.