Research workbench
AlphaFold monomer V2.0 prediction for sigma intracellular receptor 2 (Q3MHW7)
Analyse AlphaFold monomer V2.0 prediction for sigma intracellular receptor 2 (Q3MHW7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q3MHW7
- Type
- protein
- Length
- 176 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Sigma intracellular receptor 2
- UniProt
- Q3MHW7
- Pockets
- 2 · best druggability 0.70
Structure
1 distinct chain · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sigma intracellular receptor 2 | protein | 176 | 76% helix, 0% strand | Q3MHW7 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 149 | 0.70 | 0.89 | 20 | empty |
| 2 | 50 | 0.32 | 0.77 | 13 | empty |
Compared structures
- 7M94 · Bovine sigma-2 receptor bound to roluperidone · an experimental structure of the same protein · chain A against B, TM-score 0.93
- 7M94 · Bovine sigma-2 receptor bound to Roluperidone · an experimental structure of the same protein · chain A against B, TM-score 0.93
- 7M96 · Bovine sigma-2 receptor bound to Z4857158944 · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 7M93 · Bovine sigma-2 receptor bound to PB28 · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 7M93 · Bovine sigma-2 receptor bound to PB28 · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 7MFI · Bovine sigma-2 receptor bound to cholesterol · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 7MFI · Bovine sigma-2 receptor bound to cholesterol · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 7M96 · Bovine sigma-2 receptor bound to Z4857158944 · an experimental structure of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3MHW7
- Elsewhere: UniProt Q3MHW7 · AlphaFold DB Q3MHW7
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