Research workbench
AlphaFold monomer V2.0 prediction for sigma non-opioid intracellular receptor 1 (Q6DCU6)
Analyse AlphaFold monomer V2.0 prediction for sigma non-opioid intracellular receptor 1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q6DCU6
- Type
- protein
- Length
- 221 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- Sigma non-opioid intracellular receptor 1
- UniProt
- Q6DCU6
- Pockets
- 1 · best druggability 0.82
Structure
1 distinct chain · 44% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sigma non-opioid intracellular receptor 1 | protein | 221 | 44% helix, 29% strand | Q6DCU6 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.82 | 0.94 | 38 | empty |
Compared structures
- 7W2B · The closed conformation of the sigma-1 receptor from xenopus laevis · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7W2B · The closed conformation of the sigma-1 receptor from Xenopus laevis · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7W2D · The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with S1RA · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 7W2D · The closed conformation of the sigma-1 receptor from xenopus laevis complexed with S1RA · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 7W2C · The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7W2C · The closed conformation of the sigma-1 receptor from xenopus laevis complexed with PRE084 · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 7W2E · An open-like conformation of the sigma-1 receptor from Xenopus laevis · an experimental structure of the same protein · chain A against J, TM-score 0.96
- 7W2E · An open-like conformation of the sigma-1 receptor from xenopus laevis · an experimental structure of the same protein · chain A against G, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DCU6
- Elsewhere: UniProt Q6DCU6 · AlphaFold DB Q6DCU6
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