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AlphaFold monomer V2.0 prediction for S-formylglutathione hydrolase (P40363)

Analyse AlphaFold monomer V2.0 prediction for S-formylglutathione hydrolase (P40363) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P40363
Type
protein
Length
299 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
Molecule
S-formylglutathione hydrolase
UniProt
P40363
Pockets
1 · best druggability 0.30

Structure

1 distinct chain · 37% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AS-formylglutathione hydrolaseprotein29937% helix, 23% strandP40363

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1550.300.7513empty

Compared structures

  • 3C6B · Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 3C6B · Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1PV1 · Crystal Structure Analysis of Yeast Hypothetical Protein: YJG8_YEAST · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 1PV1 · Crystal structure analysis of yeast hypothetical protein: YJG8_YEAST · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 4FLM · S-formylglutathione hydrolase W197I variant containing copper · an experimental structure of the same protein · chain A against B, TM-score 0.96
  • 4FLM · S-formylglutathione Hydrolase W197I Variant containing Copper · an experimental structure of the same protein · chain A against B, TM-score 0.96
  • 4FOL · S-formylglutathione hydrolase Variant H160I · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 4FOL · S-formylglutathione hydrolase variant H160I · an experimental structure of the same protein · chain A against A, TM-score 0.94

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