UniProt P40363
S-formylglutathione hydrolase (P40363)
S-formylglutathione hydrolase (UniProt P40363), EC 3.1.1.-, 3.1.2.12: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 31 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P40363
- Protein
- S-formylglutathione hydrolase
- EC
- 3.1.1.-, 3.1.2.12
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 31 · 6 records with a druggable one
Structures
9 records of P40363 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PV1 | Crystal Structure Analysis of Yeast Hypothetical Protein: YJG8_YEAST | x-ray diffraction | A, B, C, D | — | 6 (best 0.58) |
| 1PV1 | Crystal structure analysis of yeast hypothetical protein: YJG8_YEAST | x-ray diffraction | A, B, C, D | — | 6 (best 0.58) |
| 3C6B | Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant | x-ray diffraction | A | — | — |
| 3C6B | Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant | x-ray diffraction | A | — | — |
| 4FLM | S-formylglutathione Hydrolase W197I Variant containing Copper | x-ray diffraction | A, B | CU | 3 (best 0.58) |
| 4FLM | S-formylglutathione hydrolase W197I variant containing copper | x-ray diffraction | A, B | CU | 3 (best 0.58) |
| 4FOL | S-formylglutathione hydrolase Variant H160I | x-ray diffraction | A, B, C, D | — | 6 (best 0.63) |
| 4FOL | S-formylglutathione hydrolase variant H160I | x-ray diffraction | A, B, C, D | — | 6 (best 0.63) |
| P40363 | AlphaFold monomer V2.0 prediction for S-formylglutathione hydrolase (P40363) | predicted | A | — | 1 (best 0.30) |
Ligands
- CU · Copper (II) ion · in 2 records
Experiment against prediction
- 3C6B chain A against the predicted model P40363: TM-score 1.00, RMSD 0.24 Å
- 3C6B chain A against the predicted model P40363: TM-score 1.00, RMSD 0.24 Å
- 4FOL chain C against the predicted model P40363: TM-score 1.00, RMSD 0.32 Å
- 4FOL chain C against the predicted model P40363: TM-score 1.00, RMSD 0.32 Å
- 4FOL chain A against the predicted model P40363: TM-score 1.00, RMSD 0.34 Å
- 4FOL chain A against the predicted model P40363: TM-score 1.00, RMSD 0.34 Å
- 4FLM chain B against the predicted model P40363: TM-score 1.00, RMSD 0.35 Å
- 4FLM chain B against the predicted model P40363: TM-score 1.00, RMSD 0.35 Å
- 4FOL chain D against the predicted model P40363: TM-score 1.00, RMSD 0.37 Å
- 4FOL chain D against the predicted model P40363: TM-score 1.00, RMSD 0.37 Å
Elsewhere
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