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AlphaFold monomer V2.0 prediction for protein serrate (P18168)

Analyse AlphaFold monomer V2.0 prediction for protein serrate (P18168) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P18168
Type: protein
Length: 1,404 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x15Ecc076Aef3e102dDDA7B6F6fC88A40eA84aE39
Molecule: Protein serrate
UniProt: P18168
Pockets: 5 · best druggability 0.78

Structure

1 distinct chain · 12% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein serrate	protein	1404	12% helix, 23% strand	P18168

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	753	0.78	0.82	82	empty
2	207	0.53	0.78	35	empty
3	120	0.47	0.79	15	empty
4	56	0.35	0.78	13	empty
5	109	0.35	0.73	21	empty

Modifications

Observed in the structure: 55 disulfide (disulfide).

Compared structures

7ALT · Structure of drosophila serrate C2-dsl-EGF1-EGF2 · an experimental structure of the same protein · chain A against A, TM-score 0.17
7ALT · Structure of Drosophila Serrate C2-DSL-EGF1-EGF2 · an experimental structure of the same protein · chain A against A, TM-score 0.17

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18168
Elsewhere: UniProt P18168 · AlphaFold DB P18168

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