Research workbench
AlphaFold monomer V2.0 prediction for chloride anion exchanger (P40879)
Analyse AlphaFold monomer V2.0 prediction for chloride anion exchanger (P40879) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P40879
- Type
- protein
- Length
- 764 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1a13568a7326926D3c9276C0aF18d0Aa99f8D49F
- Molecule
- Chloride anion exchanger
- UniProt
- P40879
- Pockets
- 9 · best druggability 0.73
Structure
1 distinct chain · 58% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chloride anion exchanger | protein | 764 | 58% helix, 7% strand | P40879 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 649 | 0.73 | 0.80 | 66 | empty |
| 2 | 96 | 0.73 | 0.95 | 21 | empty |
| 3 | 381 | 0.58 | 0.76 | 43 | empty |
| 4 | 388 | 0.56 | 0.74 | 38 | empty |
| 5 | 117 | 0.52 | 0.81 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7XUJ · Human SLC26A3 in complex with UK5099 · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 7XUH · Down-regulated in adenoma in complex with TQR1122 · an experimental structure of the same protein · chain A against B, TM-score 0.86
- 7XUL · Human SLC26A3 in complex with Tenidap · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 8IET · Human SLC26A3 in the apo state · an experimental structure of the same protein · chain A against B, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40879
- Elsewhere: UniProt P40879 · AlphaFold DB P40879
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