AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A0QSL8)

Structure

1 distinct chain · 28% helix, 31% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 8R2M · Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA… · an experimental structure of the same protein · chain A against B, TM-score 0.63
• 8R3M · Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA… · an experimental structure of the same protein · chain A against B, TM-score 0.63
• 8QU6 · Mycobacterium smegnatis RNA polymerase transcription initiation complex with SigmaA… · an experimental structure of the same protein · chain A against A, TM-score 0.63
• 7P5X · Mycobacterial RNAP with transcriptional activator PafBC · an experimental structure of the same protein · chain A against AB, TM-score 0.63
• 8R6P · Mycobacterium smegnatis RNA polymerase RP2-like transcription initiation complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 8R6R · Mycobacterium smegnatis RNA polymerase RP2-like transcription initiation complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.62
• 8QTI · Mycobacterium smegnatis RNAP open promoter complex with SigmaA and RbpA · an experimental structure of the same protein · chain A against A, TM-score 0.62
• 8QN8 · Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State II · an experimental structure of the same protein · chain A against A, TM-score 0.62

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0QSL8
• Elsewhere: UniProt A0QSL8 · AlphaFold DB A0QSL8