Research workbench
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF31 (Q96EP0)
Analyse AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF31 (Q96EP0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q96EP0
- Type
- protein
- Length
- 1,072 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- E3 ubiquitin-protein ligase RNF31
- UniProt
- Q96EP0
- Pockets
- 8 · best druggability 0.73
Structure
1 distinct chain · 39% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase RNF31 | protein | 1072 | 39% helix, 8% strand | Q96EP0 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 774 | 0.73 | 0.78 | 70 | empty |
| 2 | 837 | 0.71 | 0.77 | 66 | empty |
| 3 | 208 | 0.58 | 0.80 | 31 | empty |
| 4 | 286 | 0.52 | 0.74 | 31 | empty |
| 5 | 234 | 0.50 | 0.75 | 29 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6SC6 · DAB3/HOIP-rbr apo structure · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC6 · dAb3/HOIP-RBR apo structure · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC8 · DAB3/HOIP-rbr-LIGAND4 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC8 · dAb3/HOIP-RBR-Ligand4 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC5 · dAb3/HOIP-RBR-Ligand2 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC5 · DAB3/HOIP-rbr-LIGAND2 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC7 · DAB3/HOIP-rbr-LIGAND3 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC7 · dAb3/HOIP-RBR-Ligand3 · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6SC9 · DAB3/HOIP-rbr-hoipin-8 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 6SC9 · dAb3/HOIP-RBR-HOIPIN-8 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 4LJO · Structure of an active ligase (HOIP)/ubiquitin transfer complex · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 4LJO · Structure of an active ligase (HOIP)/UBIQUITIN transfer complex · an experimental structure of the same protein · chain A against A, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96EP0
- Elsewhere: UniProt Q96EP0 · AlphaFold DB Q96EP0
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