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AlphaFold monomer V2.0 prediction for 60S ribosomal protein L2-a (P0CX45)

Analyse AlphaFold monomer V2.0 prediction for 60S ribosomal protein L2-a (P0CX45) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P0CX45
Type
protein
Length
254 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5a181f8DcC204E6eA2Da8066d42059b6b014062E
Molecule
60S ribosomal protein L2-a
UniProt
P0CX45
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 9% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L2-aprotein2549% helix, 25% strandP0CX45

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1810.320.7426empty

Compared structures

  • 8CIV · Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 8CDR · Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 8CEH · Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 8CGN · Non-rotated 80S S. cerevisiae ribosome with ligands · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 7AZY · Context-specific inhibition of eukaryotic translation by macrolide antibiotics · an experimental structure of the same protein · chain A against x, TM-score 0.98
  • 8CG8 · Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 6S47 · Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 · an experimental structure of the same protein · chain A against AD, TM-score 0.98
  • 6Q8Y · Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease… · an experimental structure of the same protein · chain A against AW, TM-score 0.98
  • 8CDL · 80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 6TB3 · yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex · an experimental structure of the same protein · chain A against AW, TM-score 0.98
  • 8CCS · 80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex · an experimental structure of the same protein · chain A against EE, TM-score 0.98
  • 9F9S · Yeast SDD1 Disome with Mbf1 · an experimental structure of the same protein · chain A against Mw, TM-score 0.98

Analyse

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