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AlphaFold monomer V2.0 prediction for RAS and ef-hand domain- containing protein (Q8IZ41)

Analyse AlphaFold monomer V2.0 prediction for RAS and ef-hand domain- containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q8IZ41
Type: protein
Length: 740 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8841A75A4374915eB1e3A60827149042327e3c89
Molecule: RAS and ef-hand domain-containing protein
UniProt: Q8IZ41
Pockets: 3 · best druggability 0.47

Structure

1 distinct chain · 50% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAS and ef-hand domain-containing protein	protein	740	50% helix, 7% strand	Q8IZ41

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	132	0.47	0.78	27	empty
2	85	0.36	0.76	18	empty
3	50	0.30	0.76	9	empty

Compared structures

2P5S · RAB domain of human RASEF in complex with GDP · an experimental structure of the same protein · chain A against B, TM-score 0.21
2P5S · Rab domain of human rasef in complex with GDP · an experimental structure of the same protein · chain A against B, TM-score 0.21
2PMY · EF-hand domain of human RASEF · an experimental structure of the same protein · chain A against A, TM-score 0.09
2PMY · Ef-hand domain of human rasef · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IZ41
Elsewhere: UniProt Q8IZ41 · AlphaFold DB Q8IZ41

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