Research workbench
AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih helicase subunit xpb (Q00578)
Analyse AlphaFold monomer V2.0 prediction for general transcription and DNA repair… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q00578
- Type
- protein
- Length
- 843 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xCe4913b38f6cdd39cE5A2503280B7fe0683920B8
- Molecule
- General transcription and DNA repair factor iih helicase subunit xpb
- UniProt
- Q00578
- Pockets
- 7 · best druggability 0.79
Structure
1 distinct chain · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General transcription and DNA repair factor iih helicase subunit xpb | protein | 843 | 36% helix, 15% strand | Q00578 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 700 | 0.79 | 0.83 | 87 | empty |
| 2 | 651 | 0.77 | 0.83 | 82 | empty |
| 3 | 396 | 0.61 | 0.77 | 51 | empty |
| 4 | 139 | 0.53 | 0.80 | 24 | empty |
| 5 | 69 | 0.39 | 0.79 | 11 | empty |
Compared structures
- 7ZSB · Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 8CEO · Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 8CEN · Yeast RNA polymerase II transcription pre-initiation complex with core Mediator · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7ZS9 · Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7O4I · Yeast RNA polymerase II transcription pre-initiation complex with initial transcription… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7O4I · Yeast RNA polymerase II transcription pre-initiation complex with initial transcription… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7ZSA · Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and… · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 8UOT · Composite map of PICdeltaTFIIK form1 · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 8UMI · consensus map of PICdeltaTFIIK form1 · an experimental structure of the same protein · chain A against 7, TM-score 0.68
- 7O4L · Yeast tfiih in the expanded state within the pre-initiation complex · an experimental structure of the same protein · chain A against 7, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00578
- Elsewhere: UniProt Q00578 · AlphaFold DB Q00578
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