Research workbench
AlphaFold monomer V2.0 prediction for prostaglandin reductase 3 (Q8N4Q0)
Analyse AlphaFold monomer V2.0 prediction for prostaglandin reductase 3 (Q8N4Q0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8N4Q0
- Type
- protein
- Length
- 377 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Prostaglandin reductase 3
- UniProt
- Q8N4Q0
- Pockets
- 3 · best druggability 0.78
Structure
1 distinct chain · 32% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prostaglandin reductase 3 | protein | 377 | 32% helix, 24% strand | Q8N4Q0 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 556 | 0.78 | 0.85 | 58 | empty |
| 2 | 51 | 0.33 | 0.78 | 14 | empty |
| 3 | 65 | 0.30 | 0.74 | 13 | empty |
Compared structures
- 2C0C · Structure of the MGC45594 gene product · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2C0C · Structure of the MGC45594 gene product · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2X7H · Crystal structure of the human MGC45594 gene product in complex with fenoprofen · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 2X7H · Crystal structure of the human MGC45594 gene product in complex with fenoprofen · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 7ZEJ · Crystal structure of the human MGC45594 gene product in complex with celecoxib. · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 7ZEJ · Crystal structure of the human MGC45594 gene product in complex with celecoxib. · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2WEK · Crystal structure of the human MGC45594 gene product in complex with diclofenac · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2WEK · Crystal structure of the human MGC45594 gene product in complex with diclofenac · an experimental structure of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N4Q0
- Elsewhere: UniProt Q8N4Q0 · AlphaFold DB Q8N4Q0
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