UniProt Q8N4Q0
Prostaglandin reductase 3 (Q8N4Q0)
Prostaglandin reductase 3 (UniProt Q8N4Q0): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N4Q0
- Protein
- Prostaglandin reductase 3
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of Q8N4Q0 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2C0C | Structure of the MGC45594 gene product | x-ray diffraction | A, B | — | — |
| 2C0C | Structure of the MGC45594 gene product | x-ray diffraction | A, B | — | — |
| 2WEK | Crystal structure of the human MGC45594 gene product in complex with diclofenac | x-ray diffraction | A, B | — | — |
| 2WEK | Crystal structure of the human MGC45594 gene product in complex with diclofenac | x-ray diffraction | A, B | — | — |
| 2X1H | Crystal structure of the human MGC45594 gene product in complex with raloxifene | x-ray diffraction | A, B | — | — |
| 2X1H | Crystal structure of the human MGC45594 gene product in complex with raloxifene | x-ray diffraction | A, B | — | — |
| 2X7H | Crystal structure of the human MGC45594 gene product in complex with fenoprofen | x-ray diffraction | A, B | — | — |
| 2X7H | Crystal structure of the human MGC45594 gene product in complex with fenoprofen | x-ray diffraction | A, B | — | — |
| 7ZEJ | Crystal structure of the human MGC45594 gene product in complex with celecoxib. | x-ray diffraction | A, B | NAP, CEL | — |
| 7ZEJ | Crystal structure of the human MGC45594 gene product in complex with celecoxib. | x-ray diffraction | A, B | NAP, CEL | — |
| Q8N4Q0 | AlphaFold monomer V2.0 prediction for prostaglandin reductase 3 (Q8N4Q0) | predicted | A | — | 3 (best 0.78) |
Ligands
Experiment against prediction
- 2X7H chain A against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.20 Å
- 2X7H chain A against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.20 Å
- 2X1H chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.20 Å
- 2X1H chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.20 Å
- 2WEK chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.21 Å
- 2WEK chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.21 Å
- 2X1H chain A against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.22 Å
- 2X1H chain A against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.22 Å
- 7ZEJ chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.26 Å
- 7ZEJ chain B against the predicted model Q8N4Q0: TM-score 1.00, RMSD 0.26 Å
Elsewhere
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