Research workbench
AlphaFold monomer V2.0 prediction for platelet-activating factor receptor (P25105)
Analyse AlphaFold monomer V2.0 prediction for platelet-activating factor receptor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P25105
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- Platelet-activating factor receptor
- UniProt
- P25105
- Pockets
- 4 · best druggability 0.80
Structure
1 distinct chain · 75% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Platelet-activating factor receptor | protein | 342 | 75% helix, 3% strand | P25105 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 273 | 0.80 | 0.91 | 44 | empty |
| 2 | 214 | 0.49 | 0.75 | 30 | empty |
| 3 | 175 | 0.45 | 0.74 | 25 | empty |
| 4 | 112 | 0.40 | 0.76 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 8XYD · Structure of Platelet-activating factor receptor-G protein complex bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 5ZKQ · Crystal structure of the human platelet-activating factor receptor in complex with ABT-491 · an experimental structure of the same protein · chain A against B, TM-score 0.79
- 5ZKQ · Crystal structure of the human platelet-activating factor receptor in complex with abt-491 · an experimental structure of the same protein · chain A against B, TM-score 0.79
- 5ZKP · Crystal structure of the human platelet-activating factor receptor in complex with sr… · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 5ZKP · Crystal structure of the human platelet-activating factor receptor in complex with SR… · an experimental structure of the same protein · chain A against A, TM-score 0.75
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25105
- Elsewhere: UniProt P25105 · AlphaFold DB P25105
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