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AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-1 (P18420)

Analyse AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-1 (P18420) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P18420
Type
protein
Length
263 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xE4dDdE4F6dA9c2bAf0CCF2Ea7ebF1b7DF4f1421e
Molecule
Proteasome subunit alpha type-1
UniProt
P18420
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 32% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProteasome subunit alpha type-1protein26332% helix, 23% strandP18420

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1730.320.7416empty

Compared structures

  • 6TU3 · Rat 20S proteasome · an experimental structure of the same protein · chain A against T, TM-score 0.88
  • 6TU3 · Rat 20S proteasome · an experimental structure of the same protein · chain A against F, TM-score 0.88
  • 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against F, TM-score 0.87
  • 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against F, TM-score 0.87
  • 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against F, TM-score 0.86
  • 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against F, TM-score 0.86
  • 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against F, TM-score 0.86
  • 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against F, TM-score 0.86
  • 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against F, TM-score 0.84
  • 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against F, TM-score 0.84

Analyse

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