Research workbench
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase PRT6 (F4KCC2)
Analyse AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase PRT6 (F4KCC2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- F4KCC2
- Type
- protein
- Length
- 2,006 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- E3 ubiquitin-protein ligase PRT6
- UniProt
- F4KCC2
- Pockets
- 20 · best druggability 0.79
Structure
1 distinct chain · 50% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase PRT6 | protein | 2006 | 50% helix, 6% strand | F4KCC2 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.79 | 0.86 | 59 | empty |
| 2 | 1200 | 0.78 | 0.80 | 94 | empty |
| 3 | 800 | 0.71 | 0.77 | 92 | empty |
| 4 | 644 | 0.68 | 0.77 | 62 | empty |
| 5 | 355 | 0.65 | 0.79 | 30 | empty |
Compared structures
- 7Y6W · RRGSGG-AtPRT6 UBR box (I222) · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 7XWF · RLGSGG-AtPRT6 UBR box (highest resolution) · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 7Y6Z · RLGSGG-AtPRT6 UBR box (I222) · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 7Y70 · RLGSGG-AtPRT6 UBR box (P4332) · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 7XWE · RRGSGG-AtPRT6 UBR box · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 7Y6X · RRGSGG-AtPRT6 UBR box (P32) · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 7Y6Y · RLGSGG-AtPRT6 UBR box (C121) · an experimental structure of the same protein · chain A against B, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F4KCC2
- Elsewhere: UniProt F4KCC2 · AlphaFold DB F4KCC2
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