AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 7 (P35998)

Structure

1 distinct chain · 43% helix, 14% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 9E8H · Human proteasome in resting state conformation bound to TXNL1 in backward conformation · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 9E8I · Human proteasome in resting state conformation bound to TXNL1 in Forward conformation · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 8USB · Non-substrate-engaged human 26S proteasome with Nub1/FAT10 bound to Rpn1 · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 7W37 · Structure of USP14-bound human 26S proteasome in state EA1_UBL · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 5L4G · The human 26S proteasome at 3.9 A · an experimental structure of the same protein · chain A against H, TM-score 0.82
• 7W38 · Structure of USP14-bound human 26S proteasome in state EA2.0_UBL · an experimental structure of the same protein · chain A against A, TM-score 0.81
• 7QXN · Proteasome-ZFAND5 Complex Z+A state · an experimental structure of the same protein · chain A against A, TM-score 0.81
• 7QXX · Proteasome-ZFAND5 Complex Z+E state · an experimental structure of the same protein · chain A against A, TM-score 0.81
• 7QXP · Proteasome-ZFAND5 Complex Z+B state · an experimental structure of the same protein · chain A against A, TM-score 0.80
• 7W3I · Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 · an experimental structure of the same protein · chain A against A, TM-score 0.80
• 7QXU · Proteasome-ZFAND5 Complex Z+C state · an experimental structure of the same protein · chain A against A, TM-score 0.80
• 6MSB · Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome · an experimental structure of the same protein · chain A against A, TM-score 0.80

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P35998
• Elsewhere: UniProt P35998 · AlphaFold DB P35998