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AlphaFold monomer V2.0 prediction for listeriolysin regulatory protein (P22262)

Analyse AlphaFold monomer V2.0 prediction for listeriolysin regulatory protein (P22262) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P22262
Type
protein
Length
237 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x89fd14a6A8d52484666c2dF913a3eb8aa7B160C6
Molecule
Listeriolysin regulatory protein
UniProt
P22262
Pockets
3 · best druggability 0.66

Structure

1 distinct chain · 45% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AListeriolysin regulatory proteinprotein23745% helix, 26% strandP22262

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13300.660.8139empty
22110.480.7530empty
3660.350.7715empty

Compared structures

  • 5LEJ · The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a 30-bp… · an experimental structure of the same protein · chain A against B, TM-score 0.97
  • 5LEJ · The transcriptional regulator prfa from listeria monocytogenes in complex with a 30-bp… · an experimental structure of the same protein · chain A against B, TM-score 0.97
  • 2BGC · Prfa-G145S, a constitutive active mutant of the transcriptional regulator in… · an experimental structure of the same protein · chain A against B, TM-score 0.97
  • 2BGC · PrfA-G145S, a constitutive active mutant of the Transcriptional Regulator In… · an experimental structure of the same protein · chain A against B, TM-score 0.97
  • 5LEK · The Transcriptional Regulator PrfA-G145S mutant from Listeria Monocytogenes in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 5LEK · The transcriptional regulator prfa-G145S mutant from listeria monocytogenes in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.97

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