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AlphaFold monomer V2.0 prediction for protein phosphatase 1H (Q9ULR3)

Analyse AlphaFold monomer V2.0 prediction for protein phosphatase 1H (Q9ULR3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9ULR3
Type
protein
Length
514 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
Molecule
Protein phosphatase 1H
UniProt
Q9ULR3
Pockets
5 · best druggability 0.55

Structure

1 distinct chain · 28% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein phosphatase 1Hprotein51428% helix, 20% strandQ9ULR3

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12660.550.7733empty
22190.530.7730empty
3890.420.7820empty
4860.350.7620empty
5900.330.7315empty

Compared structures

  • 7KPR · Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution · an experimental structure of the same protein · chain A against A, TM-score 0.77
  • 7KPR · Structure of wild-type PPM1H phosphatase at 3.1 ångström resolution · an experimental structure of the same protein · chain A against A, TM-score 0.77
  • 7L4J · Crystal structure of WT PPM1H phosphatase · an experimental structure of the same protein · chain A against A, TM-score 0.76
  • 7L4J · Crystal structure of wt PPM1H phosphatase · an experimental structure of the same protein · chain A against A, TM-score 0.76
  • 7L4I · Crystal structure of a substrate-trapping variant of PPM1H phosphatase · an experimental structure of the same protein · chain A against B, TM-score 0.76
  • 7L4I · Crystal structure of a substrate-trapping variant of PPM1H phosphatase · an experimental structure of the same protein · chain A against B, TM-score 0.76
  • 7N0Z · Structure of PPM1H phosphatase with manganese ions at the active site · an experimental structure of the same protein · chain A against A, TM-score 0.76
  • 7N0Z · Structure of PPM1H phosphatase with manganese ions at the active site · an experimental structure of the same protein · chain A against A, TM-score 0.76

Analyse

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