Research workbench
AlphaFold monomer V2.0 prediction for protein phosphatase 1H (Q9ULR3)
Analyse AlphaFold monomer V2.0 prediction for protein phosphatase 1H (Q9ULR3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9ULR3
- Type
- protein
- Length
- 514 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- Protein phosphatase 1H
- UniProt
- Q9ULR3
- Pockets
- 5 · best druggability 0.55
Structure
1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein phosphatase 1H | protein | 514 | 28% helix, 20% strand | Q9ULR3 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 266 | 0.55 | 0.77 | 33 | empty |
| 2 | 219 | 0.53 | 0.77 | 30 | empty |
| 3 | 89 | 0.42 | 0.78 | 20 | empty |
| 4 | 86 | 0.35 | 0.76 | 20 | empty |
| 5 | 90 | 0.33 | 0.73 | 15 | empty |
Compared structures
- 7KPR · Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 7KPR · Structure of wild-type PPM1H phosphatase at 3.1 ångström resolution · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 7L4J · Crystal structure of WT PPM1H phosphatase · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 7L4J · Crystal structure of wt PPM1H phosphatase · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 7L4I · Crystal structure of a substrate-trapping variant of PPM1H phosphatase · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 7L4I · Crystal structure of a substrate-trapping variant of PPM1H phosphatase · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 7N0Z · Structure of PPM1H phosphatase with manganese ions at the active site · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 7N0Z · Structure of PPM1H phosphatase with manganese ions at the active site · an experimental structure of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ULR3
- Elsewhere: UniProt Q9ULR3 · AlphaFold DB Q9ULR3
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