UniProt Q9ULR3
Protein phosphatase 1H (Q9ULR3)
Protein phosphatase 1H (UniProt Q9ULR3), EC 3.1.3.16: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9ULR3
- Protein
- Protein phosphatase 1H
- EC
- 3.1.3.16
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 30 · 5 records with a druggable one
Structures
9 records of Q9ULR3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7KPR | Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution | x-ray diffraction | A, B | MG | 8 (best 0.70) |
| 7KPR | Structure of wild-type PPM1H phosphatase at 3.1 ångström resolution | x-ray diffraction | A, B | MG | — |
| 7L4I | Crystal structure of a substrate-trapping variant of PPM1H phosphatase | x-ray diffraction | A, B | MG | 6 (best 0.69) |
| 7L4I | Crystal structure of a substrate-trapping variant of PPM1H phosphatase | x-ray diffraction | A, B | MG | — |
| 7L4J | Crystal structure of WT PPM1H phosphatase | x-ray diffraction | A, B | MG | 6 (best 0.72) |
| 7L4J | Crystal structure of wt PPM1H phosphatase | x-ray diffraction | A, B | MG | — |
| 7N0Z | Structure of PPM1H phosphatase with manganese ions at the active site | x-ray diffraction | A, B | MN, MG | 5 (best 0.71) |
| 7N0Z | Structure of PPM1H phosphatase with manganese ions at the active site | x-ray diffraction | A, B | MN, MG | — |
| Q9ULR3 | AlphaFold monomer V2.0 prediction for protein phosphatase 1H (Q9ULR3) | predicted | A | — | 5 (best 0.55) |
Ligands
Experiment against prediction
- 7L4J chain B against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.81 Å
- 7L4J chain B against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.81 Å
- 7KPR chain B against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.83 Å
- 7KPR chain B against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.83 Å
- 7N0Z chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.90 Å
- 7N0Z chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.90 Å
- 7L4J chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.94 Å
- 7L4J chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.94 Å
- 7L4I chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.97 Å
- 7L4I chain A against the predicted model Q9ULR3: TM-score 0.99, RMSD 0.97 Å
Elsewhere
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