Research workbench
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase PP1-alpha catalytic subunit (P62136)
Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P62136
- Type
- protein
- Length
- 330 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- SERINE/THREONINE-protein phosphatase PP1-alpha catalytic subunit
- UniProt
- P62136
- Pockets
- 2 · best druggability 0.60
Structure
1 distinct chain · 34% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein phosphatase PP1-alpha catalytic subunit | protein | 330 | 34% helix, 17% strand | P62136 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 379 | 0.60 | 0.77 | 29 | empty |
| 2 | 95 | 0.39 | 0.77 | 18 | empty |
Compared structures
- 6ZEG · Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 6ZEG · Structure of PP1-IRSP53 chimera [PP1(7-304) + linker (G/S)X9 + IRSP53(449-465)] bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 6ZEH · Structure of PP1-spectrin alpha II chimera [PP1(7-304) + linker (G/S)x9 + spectrin alpha… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 6ZEH · Structure of PP1-spectrin alpha II chimera [PP1(7-304) + linker (G/S) X9 + spectrin alpha… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 6ZEI · Structure of PP1-IRSP53 S455E chimera [PP1(7-304) + linker (G/S)X9 + IRSP53(449-465)]… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 6ZEI · Structure of PP1-IRSp53 S455E chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)]… · an experimental structure of the same protein · chain A against B, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62136
- Elsewhere: UniProt P62136 · AlphaFold DB P62136
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