Research workbench
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pkni (P9WI69)
Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pkni… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P9WI69
- Type
- protein
- Length
- 585 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x017919F1bE1124b92211d6Ce23B1B47B990387b9
- Molecule
- SERINE/THREONINE-protein kinase pkni
- UniProt
- P9WI69
- Pockets
- 5 · best druggability 0.74
Structure
1 distinct chain · 22% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase pkni | protein | 585 | 22% helix, 23% strand | P9WI69 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 993 | 0.74 | 0.77 | 80 | empty |
| 2 | 704 | 0.71 | 0.77 | 53 | empty |
| 3 | 64 | 0.53 | 0.87 | 17 | empty |
| 4 | 125 | 0.43 | 0.76 | 22 | empty |
| 5 | 66 | 0.30 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 5M08 · Crystal structure of mycobacterium tuberculosis pkni kinase domain, C20A_R136A double… · an experimental structure of the same protein · chain A against B, TM-score 0.43
- 5M08 · Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A_R136A double… · an experimental structure of the same protein · chain A against B, TM-score 0.43
- 5XKA · Crystal structure of M.TUBERCULOSIS pkni kinase domain · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 5XKA · Crystal structure of M.tuberculosis PknI kinase domain · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 5M06 · Crystal structure of Mycobacterium tuberculosis PknI kinase domain · an experimental structure of the same protein · chain A against B, TM-score 0.42
- 5M06 · Crystal structure of mycobacterium tuberculosis pkni kinase domain · an experimental structure of the same protein · chain A against B, TM-score 0.42
- 5M07 · Crystal structure of mycobacterium tuberculosis pkni kinase domain, C20A mutant · an experimental structure of the same protein · chain A against A, TM-score 0.42
- 5M07 · Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A mutant · an experimental structure of the same protein · chain A against A, TM-score 0.42
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WI69
- Elsewhere: UniProt P9WI69 · AlphaFold DB P9WI69
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