UniProt P9WI69
Serine/threonine-protein kinase PknI (P9WI69)
Serine/threonine-protein kinase PknI (UniProt P9WI69), EC 2.7.11.1: 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P9WI69
- Protein
- Serine/threonine-protein kinase PknI
- EC
- 2.7.11.1
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 36 · 7 records with a druggable one
Structures
15 records of P9WI69 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5M06 | Crystal structure of Mycobacterium tuberculosis PknI kinase domain | x-ray diffraction | A, B | ADP, CA | — |
| 5M06 | Crystal structure of mycobacterium tuberculosis pkni kinase domain | x-ray diffraction | A, B | ADP, CA | — |
| 5M07 | Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A mutant | x-ray diffraction | A, B | NA | 5 (best 0.66) |
| 5M07 | Crystal structure of mycobacterium tuberculosis pkni kinase domain, C20A mutant | x-ray diffraction | A, B | NA | — |
| 5M08 | Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A_R136A double mutant | x-ray diffraction | A, B | — | 6 (best 0.64) |
| 5M08 | Crystal structure of mycobacterium tuberculosis pkni kinase domain, C20A_R136A double mutant | x-ray diffraction | A, B | — | — |
| 5M09 | Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A_R136N double mutant | x-ray diffraction | A, B | NA | 5 (best 0.64) |
| 5M09 | Crystal structure of mycobacterium tuberculosis pkni kinase domain, C20A_R136N double mutant | x-ray diffraction | A, B | NA | — |
| 5XKA | Crystal structure of M.tuberculosis PknI kinase domain | x-ray diffraction | A, B | — | 6 (best 0.79) |
| 5XKA | Crystal structure of M.TUBERCULOSIS pkni kinase domain | x-ray diffraction | A, B | — | — |
| 5XLL | Dimer form of M. tuberculosis PknI sensor domain | x-ray diffraction | A, B | — | 3 (best 0.66) |
| 5XLL | Dimer form of M. tuberculosis pkni sensor domain | x-ray diffraction | A, B | — | — |
| 5XLM | Monomer form of M.tuberculosis PknI sensor domain | x-ray diffraction | A, B | — | 6 (best 0.70) |
| 5XLM | Monomer form of M.TUBERCULOSIS pkni sensor domain | x-ray diffraction | A, B | — | — |
| P9WI69 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pkni (P9WI69) | predicted | A | — | 5 (best 0.74) |
Ligands
Experiment against prediction
- 5M09 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.50 Å
- 5M09 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.50 Å
- 5M07 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.57 Å
- 5M07 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.57 Å
- 5M08 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.61 Å
- 5M08 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.61 Å
- 5M06 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.69 Å
- 5M06 chain B against the predicted model P9WI69: TM-score 0.99, RMSD 0.69 Å
- 5M06 chain A against the predicted model P9WI69: TM-score 0.99, RMSD 0.71 Å
- 5M06 chain A against the predicted model P9WI69: TM-score 0.99, RMSD 0.71 Å
Elsewhere
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