Research workbench
AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (O60331)
Analyse AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 5-kinase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O60331
- Type
- protein
- Length
- 668 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9F605311B7e26e76340423EfAfbE5e2EFc7A0b7C
- Molecule
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
- UniProt
- O60331
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 23% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | protein | 668 | 23% helix, 13% strand | O60331 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.72 | 0.98 | 21 | empty |
| 2 | 388 | 0.59 | 0.75 | 45 | empty |
| 3 | 325 | 0.54 | 0.74 | 40 | empty |
| 4 | 224 | 0.49 | 0.75 | 29 | empty |
| 5 | 76 | 0.38 | 0.77 | 17 | empty |
Compared structures
- 3H1Z · Molecular basis for the association of PIPKIgamma -p90 with the clathrin adaptor AP-2 · an experimental structure of the same protein · chain A against P, TM-score 0.02
- 3H1Z · Molecular basis for the association of pipkigamma -P90 with the clathrin adaptor ap-2 · an experimental structure of the same protein · chain A against P, TM-score 0.02
- 3H85 · Molecular basis for the association of pipki gamma-P90 with the clathrin adaptor ap-2 · an experimental structure of the same protein · chain A against P, TM-score 0.01
- 3H85 · Molecular basis for the association of PIPKI gamma-p90 with the clathrin adaptor AP-2 · an experimental structure of the same protein · chain A against P, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60331
- Elsewhere: UniProt O60331 · AlphaFold DB O60331
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