Research workbench

AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory subunit 5 (O02696)

Analyse AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: O02696
Type: protein
Length: 877 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x882B14FbCEd9AA8538F421f0Fc2Be75789f3B8A0
Molecule: Phosphoinositide 3-kinase regulatory subunit 5
UniProt: O02696
Pockets: 15 · best druggability 0.76

Structure

1 distinct chain · 32% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoinositide 3-kinase regulatory subunit 5	protein	877	32% helix, 16% strand	O02696

Pockets

15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	749	0.76	0.80	56	empty
2	484	0.69	0.80	40	empty
3	406	0.58	0.75	41	empty
4	195	0.53	0.78	27	empty
5	212	0.51	0.76	25	empty

Compared structures

7MEZ · Structure of the phosphoinositide 3-kinase P110 gamma (PIK3CG) P101 (PIK3R5) complex · an experimental structure of the same protein · chain A against B, TM-score 0.57
7MEZ · Structure of the phosphoinositide 3-kinase p110 gamma (PIK3CG) p101 (PIK3R5) complex · an experimental structure of the same protein · chain A against B, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O02696
Elsewhere: UniProt O02696 · AlphaFold DB O02696

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.