Research workbench
AlphaFold monomer V2.0 prediction for pyruvate decarboxylase (Q12629)
Analyse AlphaFold monomer V2.0 prediction for pyruvate decarboxylase (Q12629) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q12629
- Type
- protein
- Length
- 563 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc2962C0395C930d314F6bC5B4EC1De06497Bd7ff
- Molecule
- Pyruvate decarboxylase
- UniProt
- Q12629
- Pockets
- 4 · best druggability 0.56
Structure
1 distinct chain · 41% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyruvate decarboxylase | protein | 563 | 41% helix, 18% strand | Q12629 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 203 | 0.56 | 0.80 | 28 | empty |
| 2 | 62 | 0.55 | 0.88 | 21 | empty |
| 3 | 238 | 0.52 | 0.76 | 36 | empty |
| 4 | 54 | 0.36 | 0.80 | 16 | empty |
Compared structures
- 2VJY · Pyruvate decarboxylase from Kluyveromyces lactis in complex with the substrate analogue… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 2VJY · Pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 2VK4 · Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 2VK4 · Crystal structure of pyruvate decarboxylase from kluyveromyces lactis · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 6EFH · Pyruvate decarboxylase from Kluyveromyces lactis soaked with pyruvamide · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 6EFH · Pyruvate decarboxylase from kluyveromyces lactis soaked with pyruvamide · an experimental structure of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12629
- Elsewhere: UniProt Q12629 · AlphaFold DB Q12629
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