Research workbench
AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (Q8DR59)
Analyse AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (Q8DR59) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8DR59
- Type
- protein
- Length
- 719 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- Penicillin-binding protein 1A
- UniProt
- Q8DR59
- Pockets
- 7 · best druggability 0.69
Structure
1 distinct chain · 40% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 1A | protein | 719 | 40% helix, 13% strand | Q8DR59 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 666 | 0.69 | 0.77 | 80 | empty |
| 2 | 360 | 0.59 | 0.76 | 42 | empty |
| 3 | 141 | 0.45 | 0.77 | 24 | empty |
| 4 | 74 | 0.36 | 0.77 | 15 | empty |
| 5 | 84 | 0.31 | 0.72 | 19 | empty |
Compared structures
- 2C5W · Penicillin-binding protein 1A (pbp-1A) acyl-enzyme complex (cefotaxime) from… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 2C5W · Penicillin-binding protein 1A (pbp-1A) acyl-enzyme complex (cefotaxime) from… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 2C6W · Penicillin-binding protein 1A (pbp-1A) from streptococcus pneumoniae · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 2C6W · Penicillin-binding protein 1A (pbp-1A) from streptococcus pneumoniae · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 2ZC6 · Penicillin-binding protein 1A (pbp 1A) acyl-enzyme complex (tebipenem) from streptococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2ZC6 · Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2ZC5 · Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (biapenem) from Streptococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2ZC5 · Penicillin-binding protein 1A (pbp 1A) acyl-enzyme complex (biapenem) from streptococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8DR59
- Elsewhere: UniProt Q8DR59 · AlphaFold DB Q8DR59
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