UniProt Q8DR59
Penicillin-binding protein 1A (Q8DR59)
Penicillin-binding protein 1A (UniProt Q8DR59): 8 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8DR59
- Protein
- Penicillin-binding protein 1A
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
9 records of Q8DR59 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2C5W | Penicillin-binding protein 1A (pbp-1A) acyl-enzyme complex (cefotaxime) from streptococcus… | x-ray diffraction | A, B | — | — |
| 2C5W | Penicillin-binding protein 1A (pbp-1A) acyl-enzyme complex (cefotaxime) from streptococcus… | x-ray diffraction | A, B | — | — |
| 2C6W | Penicillin-binding protein 1A (pbp-1A) from streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 2C6W | Penicillin-binding protein 1A (pbp-1A) from streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 2ZC5 | Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae | x-ray diffraction | A, C | — | — |
| 2ZC5 | Penicillin-binding protein 1A (pbp 1A) acyl-enzyme complex (biapenem) from streptococcus pneumoniae | x-ray diffraction | A, C | — | — |
| 2ZC6 | Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae | x-ray diffraction | A, C | — | — |
| 2ZC6 | Penicillin-binding protein 1A (pbp 1A) acyl-enzyme complex (tebipenem) from streptococcus pneumoniae | x-ray diffraction | A, C | — | — |
| Q8DR59 | AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (Q8DR59) | predicted | A | — | 7 (best 0.69) |
Experiment against prediction
- 2C6W chain B against the predicted model Q8DR59: TM-score 0.99, RMSD 0.76 Å
- 2C6W chain B against the predicted model Q8DR59: TM-score 0.99, RMSD 0.76 Å
- 2C5W chain B against the predicted model Q8DR59: TM-score 0.99, RMSD 0.87 Å
- 2C5W chain B against the predicted model Q8DR59: TM-score 0.99, RMSD 0.87 Å
- 2ZC6 chain A against the predicted model Q8DR59: TM-score 0.68, RMSD 0.31 Å
- 2ZC6 chain A against the predicted model Q8DR59: TM-score 0.68, RMSD 0.31 Å
- 2ZC5 chain A against the predicted model Q8DR59: TM-score 0.63, RMSD 0.41 Å
- 2ZC5 chain A against the predicted model Q8DR59: TM-score 0.63, RMSD 0.41 Å
- 2C5W chain A against the predicted model Q8DR59: TM-score 0.61, RMSD 0.78 Å
- 2C5W chain A against the predicted model Q8DR59: TM-score 0.61, RMSD 0.78 Å
Elsewhere
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