Research workbench
AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase PARP10 (Q53GL7)
Analyse AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q53GL7
- Type
- protein
- Length
- 1,025 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x091554B316044d26D7307E7F5d45AEFbD0138EB3
- Molecule
- Protein mono-ADP-ribosyltransferase PARP10
- UniProt
- Q53GL7
- Pockets
- 10 · best druggability 0.77
Structure
1 distinct chain · 27% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein mono-ADP-ribosyltransferase PARP10 | protein | 1025 | 27% helix, 18% strand | Q53GL7 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1111 | 0.77 | 0.79 | 84 | empty |
| 2 | 318 | 0.63 | 0.80 | 38 | empty |
| 3 | 216 | 0.62 | 0.82 | 34 | empty |
| 4 | 328 | 0.55 | 0.75 | 30 | empty |
| 5 | 162 | 0.48 | 0.77 | 23 | empty |
Compared structures
- 3HKV · Human POLY(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 3HKV · Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 5LX6 · Human PARP10 (ARTD10), catalytic fragment in complex with PARP inhibitor Veliparib · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 5LX6 · Human PARP10 (ARTD10), catalytic fragment in complex with parp inhibitor veliparib · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 6FXI · Human PARP10 (ARTD10), catalytic fragment in complex with 3-aminobenzamide and citrate · an experimental structure of the same protein · chain A against A, TM-score 0.18
- 6FXI · Human PARP10 (ARTD10), catalytic fragment in complex with 3- aminobenzamide and citrate · an experimental structure of the same protein · chain A against A, TM-score 0.18
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53GL7
- Elsewhere: UniProt Q53GL7 · AlphaFold DB Q53GL7
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