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AlphaFold monomer V2.0 prediction for otu domain-containing protein 7B (Q6GQQ9)

Analyse AlphaFold monomer V2.0 prediction for otu domain-containing protein 7B (Q6GQQ9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q6GQQ9
Type
protein
Length
843 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB1F9f6f3e842952AC4115b59A6e6F9EF45a0C86d
Molecule
Otu domain-containing protein 7B
UniProt
Q6GQQ9
Pockets
6 · best druggability 0.74

Structure

1 distinct chain · 28% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AOtu domain-containing protein 7Bprotein84328% helix, 7% strandQ6GQQ9

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18720.740.7894empty
23090.580.7728empty
3670.440.8222empty
4510.330.7814empty
5620.280.7310empty

Compared structures

  • 5LRV · Structure of CEZANNE/OTUD7B otu domain bound to LYS11-linked diubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.31
  • 5LRV · Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.31
  • 5LRU · Structure of Cezanne/OTUD7B OTU domain · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 5LRU · Structure of CEZANNE/OTUD7B otu domain · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 5LRW · Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin · an experimental structure of the same protein · chain A against C, TM-score 0.29
  • 5LRW · Structure of CEZANNE/OTUD7B otu domain bound to ubiquitin · an experimental structure of the same protein · chain A against C, TM-score 0.29

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