MolNFT v1 · #126068 · protein

Structure of CEZANNE/OTUD7B otu domain

5LRU · Otu domain-containing protein 7B: “Structure of CEZANNE/OTUD7B otu domain”. X-ray diffraction, 2 pockets (best druggability 0.58). MolNFT v1 #126068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5LRU
Type: protein
Length: 280 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Otu domain-containing protein 7B
EC: 3.4.19.12
UniProt: Q6GQQ9
Pockets: 2 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Otu domain-containing protein 7B (EC 3.4.19.12)	protein	280	39% helix, 21% strand	Q6GQQ9

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	245	0.58	0.79	41	empty
2	65	0.31	0.74	14	empty

Compared structures

5LRU · Structure of Cezanne/OTUD7B OTU domain · the same entry in another collection · chain A against A, TM-score 1.00
Q6GQQ9 · AlphaFold monomer V2.0 prediction for otu domain-containing protein 7B (Q6GQQ9) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6GQQ9
Elsewhere: RCSB PDB 5LRU · PDBe 5LRU · UniProt Q6GQQ9

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