Research workbench
AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit F (O66841)
Analyse AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit F… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O66841
- Type
- protein
- Length
- 426 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79B29126Dc4f4fA95a507313353F0220340b8df6
- Molecule
- NADH-quinone oxidoreductase subunit F
- UniProt
- O66841
- Pockets
- 4 · best druggability 0.74
Structure
1 distinct chain · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-quinone oxidoreductase subunit F | protein | 426 | 46% helix, 16% strand | O66841 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 493 | 0.74 | 0.83 | 44 | empty |
| 2 | 80 | 0.43 | 0.80 | 17 | empty |
| 3 | 54 | 0.35 | 0.78 | 12 | empty |
| 4 | 52 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 6SAQ · wild-type NuoEF from Aquifex aeolicus bound to NADH-OH · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 6SAQ · Wild-type nuoef from aquifex aeolicus bound to NADH-oh · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 9FEA · Crystal Structure of reduced NuoEF variant P228R(NuoF) from Aquifex aeolicus bound to NAD+ · an experimental structure of the same protein · chain A against D, TM-score 0.98
- 6Q9K · Crystal structure of reduced aquifex aeolicus NADH-quinone oxidoreductase subunits nuoe… · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 6Q9C · Crystal structure of aquifex aeolicus NADH-quinone oxidoreductase subunits nuoe and nuof… · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 6Q9G · Crystal structure of reduced Aquifex aeolicus NADH-qui oxidoreductase subunits NuoE G129D… · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 6Q9G · Crystal structure of reduced aquifex aeolicus NADH-quinone oxidoreductase subunits nuoe… · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 9FIH · Crystal Structure of NuoEF variant P228R(NuoF) from Aquifex aeolicus bound to NADH under… · an experimental structure of the same protein · chain A against D, TM-score 0.98
- 6Q9J · Crystal structure of reduced aquifex aeolicus NADH-quinone oxidoreductase subunits nuoe… · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 8QG1 · Crystal structure of oxidized respiratory Complex I subunits NuoEF from Aquifex aeolicus… · an experimental structure of the same protein · chain A against D, TM-score 0.98
- 6HLA · wild-type NuoEF from Aquifex aeolicus - reduced form bound to NADH · an experimental structure of the same protein · chain A against D, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O66841
- Elsewhere: UniProt O66841 · AlphaFold DB O66841
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