Research workbench
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 5 (O78756)
Analyse AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 5… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O78756
- Type
- protein
- Length
- 606 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8edD144f4ac42c0531a333DF70DD4843E3D334A9
- Molecule
- NADH-ubiquinone oxidoreductase chain 5
- UniProt
- O78756
- Pockets
- 6 · best druggability 0.57
Structure
1 distinct chain · 75% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 5 | protein | 606 | 75% helix, 4% strand | O78756 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.57 | 0.80 | 22 | empty |
| 2 | 188 | 0.54 | 0.79 | 31 | empty |
| 3 | 187 | 0.47 | 0.75 | 25 | empty |
| 4 | 94 | 0.46 | 0.79 | 20 | empty |
| 5 | 134 | 0.39 | 0.74 | 17 | empty |
Compared structures
- 6ZKR · Native complex I, OPEN3 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKR · Native complex I, open3 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKP · Native complex I, OPEN1 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKA · Membrane domain of open complex I during turnover · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKQ · Native complex I, OPEN2 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKL · Complex I inhibited by rotenone, OPEN1 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKE · Complex I during turnover, OPEN2 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKF · Complex I during turnover, OPEN3 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKF · Complex I during turnover, open3 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKD · Complex I during turnover, OPEN1 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKI · Complex I with NADH, OPEN2 · an experimental structure of the same protein · chain A against L, TM-score 0.98
- 6ZKH · Complex I with NADH, OPEN1 · an experimental structure of the same protein · chain A against L, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O78756
- Elsewhere: UniProt O78756 · AlphaFold DB O78756
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