Research workbench
AlphaFold monomer V2.0 prediction for nucleolar GTP-binding protein 2 (P53742)
Analyse AlphaFold monomer V2.0 prediction for nucleolar GTP-binding protein 2 (P53742) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P53742
- Type
- protein
- Length
- 486 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaBB96b54Dbce4a4B66B7AfA0c273A1eeC22Cd75F
- Molecule
- Nucleolar GTP-binding protein 2
- UniProt
- P53742
- Pockets
- 5 · best druggability 0.67
Structure
1 distinct chain · 43% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleolar GTP-binding protein 2 | protein | 486 | 43% helix, 9% strand | P53742 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 375 | 0.67 | 0.81 | 52 | empty |
| 2 | 248 | 0.60 | 0.80 | 34 | empty |
| 3 | 261 | 0.57 | 0.78 | 36 | empty |
| 4 | 64 | 0.42 | 0.82 | 15 | empty |
| 5 | 120 | 0.40 | 0.75 | 17 | empty |
Compared structures
- 6M62 · Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae… · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7UUI · Nucleoplasmic pre-60S intermediate of the Nog2 containing post-rotation state from a SPB1… · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7OHQ · Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7OH3 · Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7UQB · Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a… · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7UQZ · Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1… · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7V08 · Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1… · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 6YLH · Rix1-Rea1 pre-60S particle - full composite structure · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 6YLG · Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement) · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7UOO · Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 3JCT · Cryo-em structure of eukaryotic pre-60S ribosomal subunits · an experimental structure of the same protein · chain A against m, TM-score 0.66
- 7UG6 · Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 · an experimental structure of the same protein · chain A against m, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53742
- Elsewhere: UniProt P53742 · AlphaFold DB P53742
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