UniProt P53742
Nucleolar GTP-binding protein 2 (P53742)
Nucleolar GTP-binding protein 2 (UniProt P53742): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53742
- Protein
- Nucleolar GTP-binding protein 2
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 10 · 5 records with a druggable one
Structures
8 records of P53742 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | m | — | — |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | m | GTP, MG | — |
| 6N8J | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | electron microscopy | m | GTP, MG | 2 (best 0.87) |
| 7OH3 | Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae | electron microscopy | m | MG | 1 (best 0.86) |
| 7UG6 | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | electron microscopy | m | GDP, MG | 1 (best 0.85) |
| 7UOO | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | electron microscopy | m | GTP, MG, K | 1 (best 0.87) |
| 7UUI | Nucleoplasmic pre-60S intermediate of the Nog2 containing post-rotation state from a SPB1 D52A… | electron microscopy | m | MG, K, GDP | — |
| P53742 | AlphaFold monomer V2.0 prediction for nucleolar GTP-binding protein 2 (P53742) | predicted | A | — | 5 (best 0.67) |
Ligands
Experiment against prediction
- 6N8J chain m against the predicted model P53742: TM-score 0.72, RMSD 2.95 Å
- 7UUI chain m against the predicted model P53742: TM-score 0.71, RMSD 3.24 Å
- 6M62 chain m against the predicted model P53742: TM-score 0.71, RMSD 3.75 Å
- 7UOO chain m against the predicted model P53742: TM-score 0.68, RMSD 3.77 Å
- 7OH3 chain m against the predicted model P53742: TM-score 0.68, RMSD 3.73 Å
- 3JCT chain m against the predicted model P53742: TM-score 0.68, RMSD 3.63 Å
- 7UG6 chain m against the predicted model P53742: TM-score 0.68, RMSD 3.72 Å
Elsewhere
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